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What is carpal tunnel syndrome?
Carpal tunnel syndrome occurs when the median nerve, which
runs from the forearm into the hand, becomes pressed or
squeezed at the wrist. The median nerve controls sensations to
the palm side of the thumb and fingers (although not the
little finger), as well as impulses to some small muscles in
the hand that allow the fingers and thumb to move. The carpal
tunnel - a narrow, rigid passageway of ligament and bones at
the base of the hand ¾ houses the median nerve and tendons.
Sometimes, thickening from irritated tendons or other swelling
narrows the tunnel and causes the median nerve to be
compressed. The result may be pain, weakness, or numbness in
the hand and wrist, radiating up the arm. Although painful
sensations may indicate other conditions, carpal tunnel
syndrome is the most common and widely known of the entrapment
neuropathies in which the body's peripheral nerves are
compressed or traumatized.
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What are the symptoms of carpal tunnel syndrome?
Symptoms usually start gradually, with frequent burning,
tingling, or itching numbness in the palm of the hand and the
fingers, especially the thumb and the index and middle
fingers. Some carpal tunnel sufferers say their fingers feel
useless and swollen, even though little or no swelling is
apparent. The symptoms often first appear in one or both hands
during the night, since many people sleep with flexed wrists.
A person with carpal tunnel syndrome may wake up feeling the
need to "shake out" the hand or wrist. As symptoms worsen,
people might feel tingling during the day. Decreased grip
strength may make it difficult to form a fist, grasp small
objects, or perform other manual tasks. In chronic and/or
untreated cases, the muscles at the base of the thumb may
waste away. Some people are unable to tell between hot and
cold by touch.
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What are the causes of carpal tunnel syndrome?
Carpal tunnel syndrome is often the result of a combination of
factors that increase pressure on the median nerve and tendons
in the carpal tunnel, rather than a problem with the nerve
itself. Most likely the disorder is due to a congenital
predisposition - the carpal tunnel is simply smaller in some
people than in others. Other contributing factors include
trauma or injury to the wrist that cause swelling, such as
sprain or fracture; over activity of the pituitary gland;
hypothyroidism; rheumatoid arthritis; mechanical problems in
the wrist joint; work stress; repeated use of vibrating hand
tools; fluid retention during pregnancy or menopause; or the
development of a cyst or tumor in the canal. In some cases no
cause can be identified.
There is little clinical data to prove whether repetitive and
forceful movements of the hand and wrist during work or
leisure activities can cause carpal tunnel syndrome. Repeated
motions performed in the course of normal work or other daily
activities can result in repetitive motion disorders such as
bursitis and tendonitis. Writer's cramp - a condition in which
a lack of fine motor skill coordination and ache and pressure
in the fingers, wrist, or forearm is brought on by repetitive
activity - is not a symptom of carpal tunnel syndrome.
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Who is at risk of developing carpal tunnel syndrome?
Women are three times more likely than men to develop carpal
tunnel syndrome, perhaps because the carpal tunnel itself may
be smaller in women than in men. The dominant hand is usually
affected first and produces the most severe pain. Persons with
diabetes or other metabolic disorders that directly affect the
body's nerves and make them more susceptible to compression
are also at high risk. Carpal tunnel syndrome usually occurs
only in adults.
The risk of developing carpal tunnel syndrome is not confined
to people in a single industry or job, but is especially
common in those performing assembly line work - manufacturing,
sewing, finishing, cleaning, and meat, poultry, or fish
packing. In fact, carpal tunnel syndrome is three times more
common among assemblers than among data-entry personnel. A
2001 study by the Mayo Clinic found heavy computer use (up to
7 hours a day) did not increase a person's risk of developing
carpal tunnel syndrome.
During 1998, an estimated three of every 10,000 workers lost
time from work because of carpal tunnel syndrome. Half of
these workers missed more than 10 days of work. The average
lifetime cost of carpal tunnel syndrome, including medical
bills and lost time from work, is estimated to be about
$30,000 for each injured worker.
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How is carpal tunnel syndrome diagnosed?
Early diagnosis and treatment are important to avoid permanent
damage to the median nerve. A physical examination of the
hands, arms, shoulders, and neck can help determine if the
patient's complaints are related to daily activities or to an
underlying disorder, and can rule out other painful conditions
that mimic carpal tunnel syndrome. The wrist is examined for
tenderness, swelling, warmth, and discoloration. Each finger
should be tested for sensation, and the muscles at the base of
the hand should be examined for strength and signs of atrophy.
Routine laboratory tests and X-rays can reveal diabetes,
arthritis, and fractures.
Physicians can use specific tests to try to produce the
symptoms of carpal tunnel syndrome. In the Tinel test, the
doctor taps on or presses on the median nerve in the patient's
wrist. The test is positive when tingling in the fingers or a
resultant shock-like sensation occurs. The Phalen, or
wrist-flexion, test involves having the patient hold his or
her forearms upright by pointing the fingers down and pressing
the backs of the hands together. The presence of carpal tunnel
syndrome is suggested if one or more symptoms, such as
tingling or increasing numbness, is felt in the fingers within
1 minute. Doctors may also ask patients to try to make a
movement that brings on symptoms.
Often it is necessary to confirm the diagnosis by use of
electrodiagnostic tests. In a nerve conduction study,
electrodes are placed on the hand and wrist. Small electric
shocks are applied and the speed with which nerves transmit
impulses is measured. In electromyography, a fine needle is
inserted into a muscle; electrical activity viewed on a screen
can determine the severity of damage to the median nerve.
Ultrasound imaging can show impaired movement of the median
nerve. Magnetic resonance imaging (MRI) can show the anatomy
of the wrist but to date has not been especially useful in
diagnosing carpal tunnel syndrome.
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How is carpal tunnel syndrome treated?
Treatments for carpal tunnel syndrome should begin as early as
possible, under a doctor's direction. Underlying causes such
as diabetes or arthritis should be treated first. Initial
treatment generally involves resting the affected hand and
wrist for at least 2 weeks, avoiding activities that may
worsen symptoms, and immobilizing the wrist in a splint to
avoid further damage from twisting or bending. If there is
inflammation, applying cool packs can help reduce swelling.
Non-surgical treatments
Drugs - In special circumstances, various drugs can ease the
pain and swelling associated with carpal tunnel syndrome.
Nonsteroidal anti-inflammatory drugs, such as aspirin,
ibuprofen, and other nonprescription pain relievers, may ease
symptoms that have been present for a short time or have been
caused by strenuous activity. Orally administered diuretics
("water pills") can decrease swelling. Corticosteroids (such
as prednisone) or the drug lidocaine can be injected directly
into the wrist or taken by mouth (in the case of prednisone)
to relieve pressure on the median nerve and provide immediate,
temporary relief to persons with mild or intermittent
symptoms. (Caution: persons with diabetes and those who may be
predisposed to diabetes should note that prolonged use of
corticosteroids can make it difficult to regulate insulin
levels. Corticosterioids should not be taken without a
doctor's prescription.) Additionally, some studies show that
vitamin B6 (pyridoxine) supplements may ease the symptoms of
carpal tunnel syndrome.
Exercise - Stretching and strengthening exercises can be
helpful in people whose symptoms have abated. These exercises
may be supervised by a physical therapist, who is trained to
use exercises to treat physical impairments, or an
occupational therapist, who is trained in evaluating people
with physical impairments and helping them build skills to
improve their health and well-being.
Alternative therapies
- Acupuncture and chiropractic care have
benefited some patients but their effectiveness remains
unproved. An exception is yoga, which has been shown to reduce
pain and improve grip strength among patients with carpal
tunnel syndrome.
Surgery
Carpal tunnel release is one of the most common surgical
procedures in the United States. Generally recommended if
symptoms last for 6 months, surgery involves severing the band
of tissue around the wrist to reduce pressure on the median
nerve. Surgery is done under local anesthesia and does not
require an overnight hospital stay. Many patients require
surgery on both hands. The following are types of carpal
tunnel release surgery:
Open release surgery, the traditional procedure used to
correct carpal tunnel syndrome, consists of making an incision
up to 2 inches in the wrist and then cutting the carpal
ligament to enlarge the carpal tunnel. The procedure is
generally done under local anesthesia on an outpatient basis,
unless there are unusual medical considerations.
Endoscopic surgery may allow faster functional recovery and
less postoperative discomfort than traditional open release
surgery. The surgeon makes two incisions (about ½" each) in
the wrist and palm, inserts a camera attached to a tube,
observes the tissue on a screen, and cuts the carpal ligament
(the tissue that holds joints together). This two-portal
endoscopic surgery, generally performed under local
anesthesia, is effective and minimizes scarring and scar
tenderness, if any. One-portal endoscopic surgery for carpal
tunnel syndrome is also available.
Although symptoms may be relieved immediately after surgery,
full recovery from carpal tunnel surgery can take months. Some
patients may have infection, nerve damage, stiffness, and pain
at the scar. Occasionally the wrist loses strength because the
carpal ligament is cut. Patients should undergo physical
therapy after surgery to restore wrist strength. Some patients
may need to adjust job duties or even change jobs after
recovery from surgery.
Recurrence of carpal tunnel syndrome following treatment is
rare. The majority of patients recover completely.
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How can carpal tunnel syndrome be prevented?
At the workplace, workers can do on-the-job conditioning,
perform stretching exercises, take frequent rest breaks, wear
splints to keep wrists straight, and use correct posture and
wrist position. Wearing fingerless gloves can help keep hands
warm and flexible. Workstations, tools and tool handles, and
tasks can be redesigned to enable the worker's wrist to
maintain a natural position during work. Jobs can be rotated
among workers. Employers can develop programs in ergonomics,
the process of adapting workplace conditions and job demands
to the capabilities of workers. However, research has not
conclusively shown that these workplace changes prevent the
occurrence of carpal tunnel syndrome.
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What research is being done?
The National Institute of Neurological Disorders and Stroke (NINDS),
a part of the National Institutes of Health, is the federal
government's leading supporter of biomedical research on
neuropathy, including carpal tunnel syndrome. Scientists are
studying the chronology of events that occur with carpal
tunnel syndrome in order to better understand, treat, and
prevent this ailment. By determining distinct biomechanical
factors related to pain, such as specific joint angles,
motions, force, and progression over time, researchers are
finding new ways to limit or prevent carpal tunnel syndrome in
the workplace and decrease other costly and disabling
occupational illnesses.
Randomized clinical trials are being designed to evaluate the
effectiveness of educational interventions in reducing the
incidence of carpal tunnel syndrome and upper extremity
cumulative trauma disorders. Data to be collected from an
NINDS-sponsored clinical study of carpal tunnel syndrome among
construction apprentices will provide a better understanding
of the specific work factors associated with the disorder,
furnish pilot data for planning future projects to study its
natural history, and assist in developing strategies to
prevent its occurrence among construction and other workers.
Other research will discern differences between the relatively
new carpal compression test (in which the examiner applies
moderate pressure with both thumbs directly on the carpal
tunnel and underlying median nerve, at the transverse carpal
ligament) and the pressure provocative test (in which a cuff
placed at the anterior of the carpal tunnel is inflated,
followed by direct pressure on the median nerve) in predicting
carpal tunnel syndrome. Scientists are also investigating the
use of alternative therapies, such as acupuncture, to prevent
and treat this disorder.
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Where can I get more information?
For more information on neurological disorders or research
programs funded by the National Institute of Neurological
Disorders and Stroke, contact the Institute's Brain Resources
and Information Network (BRAIN) at:
BRAIN
P.O. Box 5801
Bethesda, MD 20824
(800) 352-9424
http://www.ninds.nih.gov
Information also is available from the following
organizations:
American Chronic Pain Association (ACPA)
P.O. Box 850
Rocklin, CA 95677-0850
ACPA@pacbell.net
http://www.theacpa.org
Tel: 916-632-0922 800-533-3231
Fax: 916-632-3208
National Institute of Arthritis and Musculoskeletal and Skin
Diseases (NIAMS)
National Institutes of Health, DHHS
31 Center Dr., Rm. 4C02 MSC 2350
Bethesda, MD 20892-2350
NIAMSinfo@mail.nih.gov
http://www.niams.nih.gov
Tel: 301-496-8190 877-22-NIAMS (226-4267)
Centers for Disease Control and Prevention (CDCP)
U.S. Department of Health and Human Services
1600 Clifton Road, N.E.
Atlanta, GA 30333
inquiry@cdc.gov
http://www.cdc.gov
Tel: 800-311-3435 404-639-3311/404-639-3543
Occupational Safety & Health Administration
U.S. Department of Labor
200 Constitution Avenue, NW
Washington, DC 20210
http://www.osha.gov
Tel: 800-321-OSHA (-6742)
American Academy of Orthopaedic Surgeons/ American Association
of Orthopaedic Surgeons
6300 North River Road
Rosemont, IL 60018
hackett@aaos.org
http://www.aaos.org
Tel: 847-823-7186
Fax: 847-823-8125
American Society for Surgery of the Hand
6300 North River Road
Suite 600
Rosemont, Il 60018-4256
info@assh.org
www.assh.org
Tel: 847-384-8300
Fax: 847-384-1435
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NIH Publication No. 03-4898
Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
NINDS health-related material is provided for information
purposes only and does not necessarily represent endorsement
by or an official position of the National Institute of
Neurological Disorders and Stroke or any other Federal agency.
Advice on the treatment or care of an individual patient
should be obtained through consultation with a physician who
has examined that patient or is familiar with that patient's
medical history.
All NINDS-prepared information is in the public domain and may
be freely copied. Credit to the NINDS or the NIH is
appreciated.
Last updated August 02, 2006 |
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