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Natural
Herbal Alternative Remedies & Treatments for Liver /
Cirrhosis
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Liver Dr.:
To improve functioning of the liver and promote health;
To prevent problems associated with a sluggish liver (e.g.
depressed immune systems, constant fatigue, obesity, sluggish
digestive systems, allergies, respiratory ailments, unhealthy
skin, irritability and many other health problems.) ;
To help treat liver disease and prevent further damage to the
liver in diseases like viral hepatitis, cirrhosis, fatty
liver, hemochromatosis, Alpha-1 antitrypsin deficiency and
Wilson’s disease;
To protect the healthy liver from damage caused by medications
and alcohol
To improve gall bladder functioning, reduce inflammation and
help dissipate gallstones;
To neutralize toxins and as a liver-friendly anti-oxidant,
vitamin and mineral supplement.
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The liver, the largest organ in the body, is essential in
keeping the body functioning properly. It removes or
neutralizes poisons from the blood, produces immune agents to
control infection, and removes germs and bacteria from the
blood. It makes proteins that regulate blood clotting and
produces bile to help absorb fats and fat-soluble vitamins.
You cannot live without a functioning liver.
In cirrhosis of the liver, scar tissue replaces normal,
healthy tissue, blocking the flow of blood through the organ
and preventing it from working as it should. Cirrhosis is the
twelfth leading cause of death by disease, killing about
26,000 people each year. Also, the cost of cirrhosis in terms
of human suffering, hospital costs, and lost productivity is
high.
Causes
Cirrhosis has many causes. In the United States, chronic
alcoholism and hepatitis C are the most common ones.
Alcoholic liver disease. To many people, cirrhosis of the
liver is synonymous with chronic alcoholism, but in fact,
alcoholism is only one of the causes. Alcoholic cirrhosis
usually develops after more than a decade of heavy drinking.
The amount of alcohol that can injure the liver varies greatly
from person to person. In women, as few as two to three drinks
per day have been linked with cirrhosis and in men, as few as
three to four drinks per day. Alcohol seems to injure the
liver by blocking the normal metabolism of protein, fats, and
carbohydrates.
Chronic hepatitis C. The hepatitis C virus ranks with alcohol
as a major cause of chronic liver disease and cirrhosis in the
United States. Infection with this virus causes inflammation
of and low grade damage to the liver that over several decades
can lead to cirrhosis.
Chronic hepatitis B and D. The hepatitis B virus is probably
the most common cause of cirrhosis worldwide, but it is less
common in the United States and the Western world. Hepatitis
B, like hepatitis C, causes liver inflammation and injury that
over several decades can lead to cirrhosis. Hepatitis D is
another virus that infects the liver, but only in people who
already have hepatitis B.
Autoimmune hepatitis. This disease appears to be caused by the
immune system attacking the liver and causing inflammation,
damage, and eventually scarring and cirrhosis.
Inherited diseases. Alpha-1 antitrypsin deficiency,
hemochromatosis, Wilson's disease, galactosemia, and glycogen
storage diseases are among the inherited diseases that
interfere with the way the liver produces, processes, and
stores enzymes, proteins, metals, and other substances the
body needs to function properly.
Nonalcoholic steatohepatitis (NASH). In NASH, fat builds up in
the liver and eventually causes scar tissue. This type of
hepatitis appears to be associated with diabetes, protein
malnutrition, obesity, coronary artery disease, and treatment
with corticosteroid medications.
Blocked bile ducts. When the ducts that carry bile out of the
liver are blocked, bile backs up and damages liver tissue. In
babies, blocked bile ducts are most commonly caused by biliary
atresia, a disease in which the bile ducts are absent or
injured. In adults, the most common cause is primary biliary
cirrhosis, a disease in which the ducts become inflamed,
blocked, and scarred. Secondary biliary cirrhosis can happen
after gallbladder surgery if the ducts are inadvertently tied
off or injured.
Drugs, toxins, and infections. Severe reactions to
prescription drugs, prolonged exposure to environmental
toxins, the parasitic infection schistosomiasis, and repeated
bouts of heart failure with liver congestion can all lead to
cirrhosis.
[top]
Symptoms
Many people with cirrhosis have no symptoms in the early
stages of the disease. However, as scar tissue replaces
healthy cells, liver function starts to fail and a person may
experience the following symptoms:
exhaustion
fatigue
loss of appetite
nausea
weakness
weight loss
abdominal pain
spider-like blood vessels (spider angiomas) that develop on
the skin
As the disease progresses, complications may develop. In some
people, these may be the first signs of the disease.
Complications of Cirrhosis
Loss of liver function affects the body in many ways.
Following are the common problems, or complications, caused by
cirrhosis.
Edema and ascites. When the liver loses its ability to make
the protein albumin, water accumulates in the legs (edema) and
abdomen (ascites).
Bruising and bleeding. When the liver slows or stops
production of the proteins needed for blood clotting, a person
will bruise or bleed easily. The palms of the hands may be
reddish and blotchy with palmar erythema.
Jaundice. Jaundice is a yellowing of the skin and eyes that
occurs when the diseased liver does not absorb enough bilirubin.
Itching. Bile products deposited in the skin may cause intense
itching.
Gallstones. If cirrhosis prevents bile from reaching the
gallbladder, gallstones may develop.
Toxins in the blood or brain. A damaged liver cannot remove
toxins from the blood, causing them to accumulate in the blood
and eventually the brain. There, toxins can dull mental
functioning and cause personality changes, coma, and even
death. Signs of the buildup of toxins in the brain include
neglect of personal appearance, unresponsiveness,
forgetfulness, trouble concentrating, or changes in sleep
habits.
Sensitivity to medication. Cirrhosis slows the liver's ability
to filter medications from the blood. Because the liver does
not remove drugs from the blood at the usual rate, they act
longer than expected and build up in the body. This causes a
person to be more sensitive to medications and their side
effects.
Portal hypertension. Normally, blood from the intestines and
spleen is carried to the liver through the portal vein. But
cirrhosis slows the normal flow of blood through the portal
vein, which increases the pressure inside it. This condition
is called portal hypertension.
Varices. When blood flow through the portal vein slows, blood
from the intestines and spleen backs up into blood vessels in
the stomach and esophagus. These blood vessels may become
enlarged because they are not meant to carry this much blood.
The enlarged blood vessels, called varices, have thin walls
and carry high pressure, and thus are more likely to burst. If
they do burst, the result is a serious bleeding problem in the
upper stomach or esophagus that requires immediate medical
attention.
Insulin resistance and type 2 diabetes. Cirrhosis causes
resistance to insulin. This hormone, produced by the pancreas,
enables blood glucose to be used as energy by the cells of the
body. If you have insulin resistance, your muscle, fat, and
liver cells do not use insulin properly. The pancreas tries to
keep up with the demand for insulin by producing more.
Eventually, the pancreas cannot keep up with the body's need
for insulin, and type 2 diabetes develops as excess glucose
builds up in the bloodstream.
Liver cancer. Hepatocellular carcinoma, a type of liver cancer
commonly caused by cirrhosis, starts in the liver tissue
itself. It has a high mortality rate.
Problems in other organs. Cirrhosis can cause immune system
dysfunction, leading to infection. Fluid in the abdomen (ascites)
may become infected with bacteria normally present in the
intestines. Cirrhosis can also lead to impotence, kidney
dysfunction and failure, and osteoporosis.
[top]
Diagnosis
The doctor may diagnose cirrhosis on the basis of symptoms,
laboratory tests, the medical history, and a physical
examination. For example, during a physical examination, the
doctor may notice that the liver feels harder or larger than
usual and order blood tests that can show whether liver
disease is present.
If looking at the liver is necessary to check for signs of
disease, the doctor might order a computerized axial
tomography (CAT) scan, ultrasound, magnetic resonance imaging
(MRI), or a scan of the liver using a radioisotope (a harmless
radioactive substance that highlights the liver). Or the
doctor might look at the liver using a laparoscope, an
instrument that is inserted through the abdomen and relays
pictures back to a computer screen.
A liver biopsy will confirm the diagnosis. For a biopsy, the
doctor uses a needle to take a tiny sample of liver tissue,
then examines it under the microscope for scarring or other
signs of disease.
Treatment
Liver damage from cirrhosis cannot be reversed, but treatment
can stop or delay further progression and reduce
complications. Treatment depends on the cause of cirrhosis and
any complications a person is experiencing. For example,
cirrhosis caused by alcohol abuse is treated by abstaining
from alcohol. Treatment for hepatitis-related cirrhosis
involves medications used to treat the different types of
hepatitis, such as interferon for viral hepatitis and
corticosteroids for autoimmune hepatitis. Cirrhosis caused by
Wilson's disease, in which copper builds up in organs, is
treated with medications to remove the copper. These are just
a few examples—treatment for cirrhosis resulting from other
diseases depends on the underlying cause. In all cases,
regardless of the cause, following a healthy diet and avoiding
alcohol are essential because the body needs all the nutrients
it can get, and alcohol will only lead to more liver damage.
Light physical activity can help stop or delay cirrhosis as
well.
Treatment will also include remedies for complications. For
example, for ascites and edema, the doctor may recommend a
low-sodium diet or the use of diuretics, which are drugs that
remove fluid from the body. Antibiotics will be prescribed for
infections, and various medications can help with itching.
Protein causes toxins to form in the digestive tract, so
eating less protein will help decrease the buildup of toxins
in the blood and brain. The doctor may also prescribe
laxatives to help absorb the toxins and remove them from the
intestines.
For portal hypertension, the doctor may prescribe a blood
pressure medication such as a beta-blocker. If varices bleed,
the doctor may either inject them with a clotting agent or
perform a so-called rubber-band ligation, which uses a special
device to compress the varices and stop the bleeding.
When complications cannot be controlled or when the liver
becomes so damaged from scarring that it completely stops
functioning, a liver transplant is necessary. In liver
transplantation surgery, a diseased liver is removed and
replaced with a healthy one from an organ donor. About 80 to
90 percent of patients survive liver transplantation. Survival
rates have improved over the past several years because of
drugs such as cyclosporine and tacrolimus, which suppress the
immune system and keep it from attacking and damaging the new
liver.
[top]
For More Information
American Liver Foundation (ALF)
75 Maiden Lane, Suite 603
New York, NY 10038–4810
Phone: 1–800–GO–LIVER (465–4837),
1–888–4HEP–USA (443–7872),
or 212–668–1000
Fax: 212–483–8179
Email: info@liverfoundation.org
Internet: www.liverfoundation.org
Hepatitis Foundation International
504 Blick Drive
Silver Spring, MD 20904–2901
Phone: 1–800–891–0707 or 301–622–4200
Fax: 301–622–4702
Email: hfi@comcast.net
Internet: www.hepfi.org
United Network for Organ Sharing
P.O. Box 2484
Richmond, VA 23218
Phone: 1–888–894–6361 or 804–782–4800
Internet: www.unos.org
[top]
National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892–3570
Email: nddic@info.niddk.nih.gov
The National Digestive Diseases Information Clearinghouse (NDDIC)
is a service of the National Institute of Diabetes and
Digestive and Kidney Diseases (NIDDK). The NIDDK is part of
the National Institutes of Health of the U.S. Department of
Health and Human Services. Established in 1980, the
Clearinghouse provides information about digestive diseases to
people with digestive disorders and to their families, health
care professionals, and the public. The NDDIC answers
inquiries, develops and distributes publications, and works
closely with professional and patient organizations and
Government agencies to coordinate resources about digestive
diseases.
Publications produced by the Clearinghouse are carefully
reviewed by both NIDDK scientists and outside experts.
This publication is not copyrighted. The Clearinghouse
encourages users of this publication to duplicate and
distribute as many copies as desired.
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